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AutoMDS: Automated Method Development
PDR originally developed AutoMDS to support walk-away automation in our contract purification lab in 1998.
User Interface is entirely chromatographic and not dependent on the hardware being controlled. Custom hardware drivers convert chromatographic settings and inputs to hardware commands. Methods and Sequences are always 100% transferable to other AutoMDS systems.
Method and Sequence Editors use a simple spreadsheet format with pop-outs for details: very easy to build, edit, and run large method screening sequences.
Settings can be changed while running. AutoMDS adapts appropriately and records changes.
Includes methods and sequences specifically built for your applications.
Data Processing Tool filters for best methods from your runs.
AutoMDS shows status: waiting / running / done with date/time.
Methods can contain multiple Cycles; very useful in CCC/CPC.
Often we configure using your existing pumps, detectors, etc. resulting in increased productivity for little cost.
PDR continues aggressive development of new features and conveniences.
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AutoPREP: Automated Purification
PDR originally developed AutoPREP to support walk-away automation in our contract purification lab in 1998.
AutoPREP is very easy to use for purification at any scale: milligrams to tons; 1 to 1000s of injections/collections.
User Interface is entirely chromatographic and not dependent on the hardware being controlled. Custom hardware drivers convert chromatographic settings and inputs to hardware commands. Methods and Sequences are always 100% transferable to other AutoMDS systems.
Recalculate instantly shows the result of peak detection and collection settings on test run data, eliminating the need for more test runs. Optimization is quick and visual.
Collect based on combinations of time, voltage, slope, polarity, ee, etc.
Settings can be changed while running. AutoPREP will adapt and records changes.
Injections with syringe or pump.
Status: waiting / running / done with date/ time.
PDR continues aggressive development of features and conveniences.
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AutoCCC/CPC Automatic Control
AutoCCC/CPC makes control easy and automatic. Most systems are configured to operate same as HPLC for both method development and purification, see AutoMDS and AutoPREP sections. Typical configurations treat the CCC/CPC as a column. Methods use programable Cycles to Fill, Inject, Extrude, etc.
AutoCCC/CPC can be configured for syringe or pump injections at any scale.
AutoCCC/CPC can be configured with our Eluent Mixer to screen samples against programable phase mixtures. Automating method development to run similar to HPLC, in contrast to to shake-flask techniques.
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Digital Advanced Laser Polarimeter DALP
Optical Activity Detector
DALP is a new all-digital implementation of our traditional ALP (Advanced Laser Polarimeter) that has been in production since the 1995.
DALP uses digital signal processing (DSP) with proprietary algorithms to ignore fluctuations in laser power and absorbance to consistently delivery improved sensitivity, drift, and accuracy.
PDR’s companion DALP App adjusts settings, supports user calibration, and upgrades software.
Existing analog ALPs can usually be upgraded to DALP with all-new electronics and improved capabilities for about $15K.
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Continuous Concentration Monitor CCM: “separation via math“
PDR algorithms deconvolve spectral data in real time to show concentration of each component, even if component spectra are nearly identical.
CCM can be applied at any scale from analytical using Agilent DADs to inline fiber optic spectrometers for larger flows.
CCM can also extract the spectra of unknown contaminants.
