PDR-Separations develops, manufactures, and supports advanced instruments, software, systems, and processes for automating method development, purification, and process control—at any scale.
Gary W Yanik has extensive experience developing and manufacturing advanced systems by creatively applying physics, math, engineering, and software. Talented and experienced with optics and lasers, electronics, mechanics, magnetics, thermodynamics, etc.
Gary builds mental simulations of complex systems that are surprisingly accurate then uses these mental prototypes to optimize hardware and software.
Gary studied physics, math, software, and chemistry at the U of Michigan and engineering management at Caltech. Successful developments include: measuring the g-factor of positrons; photon-counting imaging spectrometers and polarimeters to study distant galaxies; multi-sensor fusion to track missiles; laser-radar guidance systems for air and underwater applications; etc.
During the 1990’s Gary began to focus on pharmaceutical applications. First developing a laser polarimeter for HPLC/SFC and then a contract services lab specializing in chiral purifications. Gary was underwhelmed with available software and hardware, so started developing his own. AutoPDR software has a consistent chromatographic user interface with drivers that convert chromatographic parameters into hardware commands, making hardware invisible. Changes can be made while running, the system adapts, and everything is real-time. Detection and Collection algorithms are sophisticated, flexible, and robust. Gary started deconvolution algorithm development In 1998. Chiral deconvolution was added to AutoPDR in 2000 and spectral deconvolution in 2020. Gary also developed a family of enabling hardware modules: injectors, collectors, selectors, universal valve controllers, etc. Gary has hands-on experience with HPLC/UHPLC, SFC, CCC/CPC, SMB/MCC, and PAT applications.
