We develop flow charts for processing compounds along a deterministic path. Flow charts are reviewed and incrementally optimized as we gain more experience and bring more capability online. We pay particular attention to how quickly jobs move through the lab and use total elapsed time from receipt to shipment as our primary metric, without sacrificing quality.
Studying the flow of jobs through our lab clearly indicates that rotovap time is about equivalent to prep separation/collection time but method development and scale up studies take significantly longer. We focused our product development on automating method development and prep peak collection.