{"id":1515,"date":"2023-05-19T05:53:12","date_gmt":"2023-05-19T10:53:12","guid":{"rendered":"https:\/\/pdr-separations.com\/?p=1515"},"modified":"2023-08-21T12:01:00","modified_gmt":"2023-08-21T17:01:00","slug":"autolab-hplc-autolab-hplc-a-fast-response-purification-lab-supporting-medicinal-chemistry-inside-a-large-pharmaceutical-company","status":"publish","type":"post","link":"https:\/\/pdr-separations.com\/?p=1515","title":{"rendered":"AutoLAB-HPLC- A fast-response purification lab supporting medicinal chemistry inside a large pharmaceutical company"},"content":{"rendered":"\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-02684f8b wp-block-columns-is-layout-flex\" style=\"margin-top:0px;margin-bottom:0px;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading has-medium-font-size\"><strong>PROBLEM<\/strong><\/h2>\n\n\n\n<pre class=\"wp-block-preformatted\">The purification lab was struggling to processes material quickly enough, staff was overwhelmed, and upper management wanted the lab to \u201cdo more with less\u201d<\/pre>\n\n\n\n<h3 class=\"wp-block-heading has-medium-font-size\" id=\"block-1a4c3a28-c6af-4e7e-a12e-47e90f839061\"><strong>GOALS\/SOLUTIONS<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The company\u2019s lab manager needed to increase throughput, reduce lab size, and reduce staff.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At first these collective goals seemed unachievable. After discussions with PDR-Separations the company decided to have PDR-Separations reconfigure the company\u2019s Agilent HPLC systems to operate with PDR-Separations\u2019 automation software and hardware.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The reconfigured Agilent analytical method development systems now run automated screening sequences written by PDR-Separations using PDR-Separations\u2019 AutoMDS software with Gradient Mixers and Column Selectors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The reconfigured Agilent semi-prep purification systems now run automated purification methods using PDR-Separations\u2019 AutoPREP software with Injector\/Collector modules.<\/p>\n\n\n\n<h3 class=\"wp-block-heading has-medium-font-size\"><strong>BENEFITS\/ACHIEVMENTS<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Results provided by the reconfigured HPLC systems were impressive.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Samples were processed faster and more deterministically. Because PDR-Separations\u2019 lab automation software was easy to use, did not require much attention, and was common to all systems staff had more time for other tasks<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By operating the automated systems 24\/7 the company was able to eliminate some systems resulting in reduced lab space. Overall results show the Lab now processes 5 times more samples in 70% of the space with 80% of the previous staff.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The no longer overloaded staff are able to do more research, attend meetings and write reports.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The combination of a new operating procedure, better automation software, and enabling automation hardware required a few months to adapt but everyone is much happier now, including upper management.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The cumulative benefit of improved procedures with better automation software and automation hardware resulted in a much better ROI than expected.<\/p>\n\n\n\n<div class=\"wp-block-essential-blocks-button\"><div class=\"eb-parent-wrapper eb-parent-eb-button-m6fqsga \"><div class=\"eb-button-wrapper eb-button-alignment eb-button-m6fqsga\"><div class=\"eb-button\"><a class=\"eb-button-anchor\" href=\"https:\/\/www.youtube.com\/watch?v=QuOb2p0-9SU\" target=\"_blank\" rel=\"noopener\">View Video<\/a><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-548190a8 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-essential-blocks-button\"><div class=\"eb-parent-wrapper eb-parent-eb-button-ud0nnzo \"><div class=\"eb-button-wrapper eb-button-alignment eb-button-ud0nnzo\"><div class=\"eb-button\"><a class=\"eb-button-anchor\" href=\"https:\/\/pdr-separations.com\/wp-content\/uploads\/AutoLAB-HPLC-2023-05-17.pdf\" target=\"_blank\" rel=\"noopener\">Download PDF<\/a><\/div><\/div><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-button\"><div class=\"eb-parent-wrapper eb-parent-eb-button-7wzbydk \"><div class=\"eb-button-wrapper eb-button-alignment eb-button-7wzbydk\"><div class=\"eb-button\"><a class=\"eb-button-anchor\" href=\"https:\/\/pdr-separations.com\/?page_id=1357\" rel=\"noopener\">Return to Case Studies<\/a><\/div><\/div><\/div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>PROBLEM The purification lab was struggling to processes material quickly enough, staff was overwhelmed, and upper management wanted the lab to \u201cdo more with less\u201d GOALS\/SOLUTIONS The company\u2019s lab manager needed to increase throughput, reduce lab size, and reduce staff. At first these collective goals seemed unachievable. After discussions with PDR-Separations the company decided to [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-1515","post","type-post","status-publish","format-standard","hentry","category-case-studies"],"_links":{"self":[{"href":"https:\/\/pdr-separations.com\/index.php?rest_route=\/wp\/v2\/posts\/1515","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdr-separations.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pdr-separations.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pdr-separations.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/pdr-separations.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1515"}],"version-history":[{"count":15,"href":"https:\/\/pdr-separations.com\/index.php?rest_route=\/wp\/v2\/posts\/1515\/revisions"}],"predecessor-version":[{"id":1564,"href":"https:\/\/pdr-separations.com\/index.php?rest_route=\/wp\/v2\/posts\/1515\/revisions\/1564"}],"wp:attachment":[{"href":"https:\/\/pdr-separations.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1515"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pdr-separations.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1515"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pdr-separations.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}